Detalhe da pesquisa
1.
Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors.
Bioorg Med Chem
; 28(15): 115600, 2020 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32631571
2.
Biased Agonist TRV027 Determinants in AT1R by Molecular Dynamics Simulations.
J Chem Inf Model
; 59(2): 797-808, 2019 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-30668103
3.
Inhibition of Porcine Aminopeptidase M (pAMP) by the Pentapeptide Microginins.
Molecules
; 24(23)2019 Nov 29.
Artigo
Inglês
| MEDLINE | ID: mdl-31795383
4.
Convergent QSAR studies on a series of NK3 receptor antagonists for schizophrenia treatment.
J Enzyme Inhib Med Chem
; 31(2): 283-94, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-25856571
5.
Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.
Int J Mol Sci
; 15(4): 5821-37, 2014 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-24714090
6.
Convergent QSAR Models for the Prediction of Cruzain Inhibitors.
ACS Omega
; 8(42): 38961-38982, 2023 Oct 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37901514
7.
Machine learning methods applied for the prediction of biological activities of triple reuptake inhibitors.
J Biomol Struct Dyn
; 41(20): 10277-10286, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36546689
8.
Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design.
Pharmaceuticals (Basel)
; 16(3)2023 Mar 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36986527
9.
Aporphine and isoquinoline derivatives block glioblastoma cell stemness and enhance temozolomide cytotoxicity.
Sci Rep
; 12(1): 21113, 2022 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36477472
10.
Insights into Newly Approved Drugs from a Medicinal Chemistry Perspective.
Mini Rev Med Chem
; 21(16): 2227-2248, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33634755
11.
Hydroquinone Exposure Worsens Rheumatoid Arthritis through the Activation of the Aryl Hydrocarbon Receptor and Interleukin-17 Pathways.
Antioxidants (Basel)
; 10(6)2021 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34200499
12.
QSAR studies on the human sirtuin 2 inhibition by non-covalent 7,5,2-anilinobenzamide derivatives.
J Biomol Struct Dyn
; 38(2): 354-363, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30789810
13.
Targeting the Plasmodium falciparum plasmepsin V by ligand-based virtual screening.
Chem Biol Drug Des
; 93(3): 300-312, 2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30320974
14.
Advances and Challenges in Drug Design of PPARδ Ligands.
Curr Drug Targets
; 19(2): 144-154, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-28413978
15.
Identification, Characterization and Molecular Modelling Studies of Schistosoma mansoni Dihydrofolate Reductase Inhibitors: From Assay Development to Hit Identification.
Curr Top Med Chem
; 18(5): 406-417, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29741139
16.
Studies of Staphylococcus aureus FabI inhibitors: fragment-based approach based on holographic structure-activity relationship analyses.
Future Med Chem
; 9(2): 135-151, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28128024
17.
Studies of Staphylococcus aureus FabI inhibitors: fragment-based approach based on holographic structure-activity relationship analyses.
Future Med Chem
; 9(2): 135-151, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-28128979
18.
Fragment-based drug discovery as alternative strategy to the drug development for neglected diseases.
Chem Biol Drug Des
; 90(6): 1067-1078, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28547936
19.
An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors.
Eur J Med Chem
; 132: 322-332, 2017 May 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28407565
20.
The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches.
PLoS One
; 12(6): e0179174, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28594906